Routine analysis of bacteria in cattle and badgers could help manage early spread of costly disease, research shows.
The novel use of genetic contact tracing to identify the source of a bovine tuberculosis outbreak could signal a new approach in managing the disease, a study suggests.
In response to a rise in bovine tuberculosis (TB) rates among wildlife in an area of East Cumbria in England with no previous infections, experts examined the DNA of the bacteria that causes the disease taken from cows and badgers that had tested positive.
All bacteria were found to be closely related to each other, pointing to a single purchase of cattle as the most likely source of infection.
The outbreak began with an infected cow brought to a farm in the region from Northern Ireland, according to the research.
Disease passed among cattle, infecting an increasing number of cows, then spread throughout the local badger population, before being passed back to cows in a cycle of infection.
Tracing infection spread
Experts from the Universities of Edinburgh and York, University College Dublin, and the UK Animal and Plant Health Agency developed a method of tracking the outbreak by integrating genetic data with spatial locations and contact tracing. This allowed them to compare small changes in the DNA as it spread from one animal to the next.
Experts suggest that their approach is an effective way to model the spread of infectious disease, and might be applied to understand the complex spread patterns of other diseases.
Scientists say routine monitoring of both cows and badgers could help to manage early outbreaks of the disease, for which control measures cost £100 million each year in England alone.
The findings could help manage outbreaks of bovine TB, an infectious respiratory disease of cattle that is mainly spread through particles in the air. It is caused by the bacterium Mycobacterium bovis, which can also infect and cause disease in other mammals, including humans, deer, wild boar, goats, pigs, cats and dogs.
(November 16, 2021. From “ The Cattle Site” )
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Post time: Nov-16-2021