Tetraoxynide 3400
Composition
Each bolus contains
Tetramisole HCl 2000mg
Oxyclozanide 1400mg
Excipient q.s.
Oxyclozanide is bisphenolic compound active against adult liver flukes in Cattle. Following absorption this drug reaches highest concentrations in liver, kidney and intestines and is excreted as an active glucuronide metablite. Oxyclozanide is an uncoupler of oxidative phosphorylation. Tetramisole hydrochloride is antinematodal drug with abroad spectrum activity against gastro-intestinal and lungworms. Tetramisole hydrochloride has a paralyzing action on nematodes, due to sustained muscle contraction.
Indications
TETRAOXYNIDE 3400 mg is a broad-spectrum anthelmintic for use in the treatment and control of gastro-intestinal and pulmonary nematodes infections and chronic fascioliasis in cattle.
- Gastrointestinal worm: Haemonchus spp., Ostertagia spp., Nematodirus spp., Trichostrongylus spp., Cooperia spp., Bunostomum spp., Oesophagostomum spp.
- Lungworms: Dictyocaulus spp.
-Liver Flukes: Fasciola Hepatica & Fasciola Gigantica.
Dosage and administration
One bolus per 150kg body weight and it is given by oral route.
Side effects
May cause occasional diarrhea, inappetence, frothing, salivation and respiratoty distress. Muzzle-foaming or hyper salivation, excitement or trembling, lip-licking and head shaking. These effects are generally noted with higher than recommended doses or ifis used concomitantly with carbacholine and organophosphates such as diazinon, etc. Symptoms generally subside within 2 hours.
Over dosages
There is good tolerance but keep the prescribed dose to avoid side effects.
Warnings
Do not treat animals during the first 45 days of pregnancy.
Do not give more than five boli at a time.
Withdrawal period
Meat: 28 days
Milk: 3 days
Storage
Store in a cool and dry place below 30C, protect from light.
Validity
4 years.





