SDtong

It is a clear, colorless to pale yellow liquid.

Each ml contains Sulfadiazine 200mg, Trimethoprim 40mg.

Sulfadiazine (SDZ) inhibits the incorporation of para-aminobenzoic acid into folic acid and trimethoprim (TMP) inhibits the enzyme dihydrofolate reductase(DHFR) which converts dihydrofolic acid into tetrahydrofolic acid. TMP and SDZ act together synergistically with a double-blockade mode of action. The combination is bactericidal, inhibiting sequential steps in the synthesis of purines which are required for DNA synthesis. TMP/SDZ combinations have a broad bactericidal action against many Gram-positive and Gram-negative aerobic bacteria and a large proportion of anaerobic bacteria.

Treatment of infections caused by, or associated with, organisms sensitive to the trimethoprim-sulfadiazine combination.

For intramuscular, intravenous or subcutaneous use.
To ensure a correct dosage, the body weight of animals to be treated should be determined as accurately as possible.
Cattle and pigs: The recommended dose rate is 2.5 mg trimethoprim / 12.5 mg sulfadiazine per kilogram body weight (1 ml product per 16 kg body weight) by intramuscular or slow intravenous injection, once daily until 2 days after symptoms resolve up to a maximum of 5 days. The maximum intramuscular volume of injection per injection site is 5 ml for pigs and 15 ml in cattle. The veterinary medicinal product may be administered by intravenous injection when blood levels of trimethoprim and sulfadiazine are required more rapidly. 
Dogs and cats: The recommended dose rate is 5 mg trimethoprim / 25 mg sulfadiazine per kilogram body weight (1 ml product per 8 kg body weight), by subcutaneous injection only, once daily until 2 days after symptoms resolve up to a maximum of 5 days The recommended injection site in dogs is the loose skin at the top of the neck.

Do not use in case of hypersensitivity to the active substances or to any of the excipients.
Do not use in animals with severe liver or renal damage or blood dyscrasias. 
Do not use in case of reduced water intake or losses of body fluid.

Anaphylactic shock (potentially fatal) has been observed on rare occasions (more than 1 but less than 10 animals in 10,000 animals treated) following administration of potentiated sulphonamide preparations, mostly after intravenous injection. For intravenous administration, the product should be warmed to body temperature and injected slowly over as long a period as is reasonably practical. At the first sign of intolerance the injection should be interrupted and shock treatment initiated.

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.

Cattle:
Meat and offal: 12 days; Milk: 48 hours.
Pigs:
Meat and offal: 20 days.

Available in 100ml bottle.

Store in a cool and dry place below 30℃, protect from light.
Keep out of reach of children.

3 years.