Clinical Application of Doramectin

Many livestock farmers are often confused when choosing anthelmintic drugs during the breeding and reproduction stages of their animals. They are unsure of what to choose and even hesitate to try some new medications. This leads to prolonged use of traditional deworming methods (such as trichlorfon, niclosamide, etc.). These methods might achieve the desired deworming "effect" on a small scale. However, when used on a large scale, various issues arise, such as inadequate coverage, frequent occurrences of abortion, poisoning, and more. Choosing a convenient and effective deworming drug is something worth considering and reflecting on during the farming process.

When using anthelmintic drugs, timing and seasonal coordination can yield better results. First, let's get to know doramectin. Doramectin is a new-generation antiparasitic drug. Compared to other commercial ivermectin products, doramectin has a broader antiparasitic spectrum (covering all external parasites and internal nematodes), better efficacy, and a longer duration of action to prevent reinfection by parasites. It is currently the best and most promising new veterinary antiparasitic drug globally. Doramectin injection is administered intramuscularly, with a single injection providing effective protection for several weeks.

When to Use:

It is recommended to deworm breeding animals 2-3 times a year and fattening animals twice a year, ideally in March-April, June-August, or July-September. For grazing animals, it is suggested to deworm at least twice a year, during the spring and autumn protection periods.

1. Breeding Females: Safe to use 30 days before or after mating, 20 days before delivery, and 15 days after delivery, with no adverse side effects from the drug itself.

2. Dairy Animals: The recommended time for use is 60-30 days before delivery. This ensures the animals are not harmed by parasites and prevents drug residues in milk.

3. Fattening Animals: Administer once after weaning, with a second dose 2-3 months later. This reduces the impact of parasites that absorb nutrients and damage the intestines.

4. Usage Method: Intramuscular injection, 1 ml per 33 kg of body weight. Provides effective protection for 120 days.

Frequently Asked Questions

1. Does it affect milk and lactation?
   Doramectin has no direct impact on milk or lactation, does not reduce milk production, and does not alter the nutritional content of milk. However, using it during lactation can result in short-term residues in milk. Therefore, it is recommended to use it at least 20 days before delivery to avoid drug residues and reduce post-delivery stress on the animal.
2. Can it be used on recently bred females?
   It can be used, but it is not recommended to use it within 15 days of mating, as all chemical anthelmintic drugs are antibiotics and have a mild "anti-inflammatory" effect. There is a 1/100 chance of inhibiting embryo implantation. However, this probability is minimal and not generally significant if deworming is done in batches.
3. Can it be used on heavily pregnant females?
   It can be used, but the expected delivery date of the animal should be considered. If less than 20 days remain before delivery, it is not recommended, not due to the drug itself, but because animals at this stage are more susceptible to external stimuli, leading to stress reactions such as constipation, loss of appetite, premature delivery, and lack of milk. If necessary, it is recommended to administer the drug when the animal is on the birthing bed.