Chongqing Fangtong Animal Pharmaceutical Co.,Ltd
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Mastong 3

Compound Amoxicillin Intramammary Infusion

Commercial Presentation:

    • 3g

    Composition

    Each syringe (3g) contains:

    Amoxicillin (as trihydrate) .....................0.2g

    Sulbactam (as sodium).......................0.05g

    Prednisolone.......................................0.01g

    Indications

    Mastong 3 is indicated in treatment of bovine mastitis due to Gram-positive and Gram-negative bacteria in lactating cow.

    Dosage and administration

    Milk out udder completely. Wash udder and teats thoroughly with warm water containing a suitable dairy antiseptic. Dry thoroughly. Clean and disinfect the teat. Remove the syringe tip cover and insert the tip of the syringe into the teat orifice. Express the suspension into the quarter with gentle and continuous pressure. Withdraw the syringe and grasp the end of the teat firmly. Massage the medication up into the milk cistern.

    For optimum response, the drug should be administered by intramammary infusion in each infected quarter as described above. Treatment should be repeated at 12-hour intervals for a total of 3 doses. At the next routine milking after the last dose, the treated quarter should be milked out and the milk discarded.

    Pharmacological Action

    Amoxicillin is a broad-spectrum antibiotic that exerts a bactericidal effect by inhibiting bacterial cell wall synthesis. It has bactericidal activity against a variety of Gram-positive and Gram-negative bacteria that cause mastitis, such as Staphylococcus, Streptococcus and Escherichia coli. Sulbactam sodium is an irreversible competitive β-lactamase inhibitor that can inhibit the destruction of β-lactam antibiotics by β-lactamase II, III, IV, and V, thereby enhancing the antibacterial effect of β-lactam antibiotics. Prednisolone has an anti-inflammatory effect, which helps to reduce inflammation and tissue swelling and promote the recovery of mastitis.

    Adverse Reactions

    No adverse reactions were observed when used at the recommended dose.

    Precautions

    1. This product is intended for use in dairy cattle only. Cattle that have been treated with this product are not intended for human consumption.

    2. Research on residual limits of sulbactam in milk is insufficient, pay attention to the risks when use.

    3. Personnel who suffer penicillin allergy should avoid contact with this product.

    4. Users of this product should take protective measures to avoid direct contact.

    Withdrawal period

    28 days for cattle; 60 hours for weaning period.

    Presentation

    3g : 0.2 g (as C16H19N3O5S) + 0.05 g (as C8H11NO5S) + 0.01 g (as C21H28O5)/syringe

    Storage

    Do not store below 30°C. Protect from light.

    Validity

    3 years