Flugtong
COMPOSITION
Each sponge contains flugestone acetate 40 mg (equivalent to flugestone 35.8mg).
Character
White cylindrical polyester polyurethane medicated sponge equipped with string.
Indications
Sex hormone drug. For prevention of abortion.
Pharmacology
Flugestone acetate is a synthetic analogue of progesterone. It is approximately 20 fold more potent than progesterone and displays progestational activity but no antiprogestational, anti-androgenic or androgenic properties together with a low glucocorticoid activity.
Owing to its binding to the progesterone receptors, flugestone acetate acts by negative feed back on the hypothalamo-pituitary axis, suppressing pituitary release of gonadotropins and therefore terminal follicular growth and ovulation.
Indication
In ewes and ewe lambs, in combination with PMSG (Pregnant Mare Serum
Gonadotropin)
- Induction and synchronization of oestrus and ovulation (non cycling ewes
during seasonal anoestrus and ewe lambs).
- Synchronization of oestrus and ovulation (cycling ewes and ewe-lambs).
Dosage and Administration
The dose is one sponge per animal irrespective of body weight, breed, type (dairy or meat) and season.
The sponge is inserted intra-vaginally using an applicator.
Duration of sponge residence is 14 days. At the end of the administration period, the sponge is gently removed by pulling on its string.
To obtain an optimal synchronization of ovulation, an intra-muscular injection of PMSG is recommended (i.m.) at the time of sponge removal.
In case fixed time artificial insemination is applied, it is recommended to perform it 55 h after sponge removal.
Use during pregnancy, lactation or lay
Pregnancy and lactation:
The use is not recommended during pregnancy.
Can be used during lactation.
Interaction with other medicinal products and other forms of interaction
The sponges should not be used in conjunction with alcohols, cresols, phenols, sheep dips or similar disinfectants.
Special precautions for use
Special precautions for use in animals:
- The repeated treatment with the product combined with PMSG may trigger the appearance of PMSG antibodies in some ewes. This in turn may affect the time of ovulation and result in reduced fertility when combined with fixed time artificial insemination at 55h following sponge removal.
- The repeated use of sponges within one year has not been studied.
- The use of a vaginal applicator designed for ewes or ewe lambs is recommended to correctly insert sponges and to avoid vaginal injuries.
Special precautions to be taken by the person administering the veterinary medicinal product to animals:
Personal protective equipment consisting of single use gloves should be worn when handling the veterinary medicinal product.
The veterinary medicinal product should not be administered by pregnant women or women suspected to be pregnant.
Direct contact with the skin should be avoided.
If accidental contact with the skin occurs, wash the affected zone with soap and water.
Wash hands after treatment and before meals.
Human exposure to this product can affect fertility.
Withdrawal Period
Meat and offal: 2 days after withdrawal of sponges.
Milk: zero hours, including the treatment time.
Presentation
Each bag contains 10 sponges, 25 sponges or 50 sponges.
Storage
Store in a dry place not above 25℃,in the original package, protect from light.
Once the bag is opened, any unused product should be discarded.
Keep out of reach of children.
Validity
3 years.










