Butatong
Composition
Each ml contains Dosage and administration Buparvaquone 50mg
Pharmacological properties
Buparvaquone is a hydroxynaphthoquinone, active against the schizont and piroplasm stages of Theileria spp. It can be used for the treatment of clinically sick animals but also for prevention during incubation in all in-contact animals before showing clinical signs. Buparvaquone is a poorly soluble naphthaquinone antiparasitic used in veterinary medicine, and it has potential for treatment of human leishmaniasis or kala-azar. Buparvaquone is a second-generation hydroxynaphthoquinone, effective in the control and prophylaxis of all forms of theileriosis. It has been tested extensively against Theileria annulata, T: parvaand T: sergenti, both in laboratory studies and in field trials, and it has undergone a rigorous programme of toxicology and safety studies.
Indication
Butatong is indicated for the treatment of theileriosis (East Coast fever, Corridor Disease) in cattle caused by Theileria parva parva, Theileria parva bovis, Theileria parva Lawrencei. Theileria annulata, Theileria mutans and Theileria orientalis sergenti.
Buparvaquone is an hydroxynaphthoquinone, active against the schizont and piroplasm stages of Theileria spp. It can be used for the treatment of clinically sick animals but also for prevention during incubation in all in-contact animals before showing clinical signs.
Dosage and Administration
2.5 mg/ kg body weight or 1 ml Butatong per 20 kg body weight by intramuscular injection. In severe cases a second identical dose may be injected 48-72hoursafter the first injection.
Normal aseptic precautions should be taken.
If more than 10 ml is to be injected, the total volume should be divided over two injection sites, one on each site of the neck.
Special warnings
No more than 10 ml should be injected into a single site. When the dose volume exceeds 10 ml the required dose should be split and injected into separate sites in the neck. In severe cased where a second treatment is necessary, this should be injected at a separate site, preferably on the opposite side of the neck.
Contraindications
Due to the inhibiting effects of theileriosis on the immune system, vaccination should be delayed until the animal has recovered from theileriosis. Intravenous or subcutaneous injections are contra-indicated.
Adverse Reactions
Localised, painless, oedematous swelling may occasionally be seen at the injection site.
Use during pregnancy, lactation or lay
Milk taken from lactating animals during the 48 hours immediately following treatment with Buparvaquone injection should not be used for human consumption.
Interaction
Not data available.
Overdose
Do not exceed stated dose.
Incompatibilities
In the absence of compatability studies, this veterinary medicinal product should not be mixed with other veterinary medicinal products.
Withdrawal period(s)
Meat: 42 days.
Milk: 48 hours.
Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products
Unused product or waste material should be disposed of in accordance with current practice for pharmaceutical waste under national waste disposal regulations.
Presentation
Available in 50ml and 100ml bottle.
Storage Condition
Do not store above 30℃, store in a dry place. Protect from light.
Keep out of reach of children.
Validity
3 years.





